Justin Brown


Associate Professor
Year Started at JMU: 2006
Contact Info

Research Description

Sudden Infant Death Syndrome (SIDS) is a leading cause of post neonatal infant mortality. Abnormal development in serotonin secreting neurons in select brainstem areas may be at the cause. I am interested in exploring how brainstem serotonin helps coordinate cardiovascular and thermoregulatory protective responses to stress. I am also interested in how environmental stress, like hypoxia or thermal stress, affects the body. This has numerous applications for animal care and post-surgical recovery clinically.

  • Human Physiology (BIO 270)
  • Pathophysiology for Physician Assistants (BIO 516 and BIO 517)
  • Introductory Neuroscience (BIO301)

Office Hours

  • PhD in Physiology, 2006, East Carolina University
  • BS in Biology/Pre-Medicine, 1997, Eastern Mennonite University
  • Le, NMP, Cockburn CL, Nowell KN, Brown JW. Activation of GABAA or 5HT1A receptors in the raphé pallidus abolish the cardiovascular responses to exogenous stress in conscious rats. Brain Research Bulletin 86 (2011) 360– 366. DOI:10.1016/j.brainresbull.2011.09.018.
  • Le NMP, Brown JW. Effect of Thermopreference on Circadian Thermoregulation in Sprauge-Dawley and Fisher 344 Rats.Journal of Thermal Biology 37 (2012) 309–315. DOI: 10.1016/j.jtherbio.2011.09.006.
  • Darnall RA, Harris MB, W H Gill, Hoffman JM, Brown JW, Niblock MM. Inhibition of Serotonergic Neurons in the Nucleus Paragigantocellularis Lateralis Disrupts Sleep Architecture and Decreases REM Sleep in the Piglet: Implications for the Sudden Infant Death Syndrome. Journal of Neuroscience 25:8322-8332. 2005.

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