Lewis

 

Associate Professor, Organic Chemistry

Year Started at JMU: 1999

lewissb@jmu.edu

Contact Info

Research Description

Research in the Lewis group centers around the synthesis, characterization, and mechanistic studies into the formation of 1,3-difluorobenzene compounds.  These 1,3-difluorobenzenes are produced from the reaction between substituted cyclobutenes and difluorocarbene.  Given that cyclobutenes are not generally readily available compounds, much time and effort is expended toward the synthesis and characterization of appropriate cyclobutene molecules to study with difluorocarbene.

Related Scholarship
  • Synthesis of 1,3-difluorobenzenes from one-pot reactions of cyclobutenes with difluorocarbene
  • Synthesis and mechanistic studies using phenyl cations generated from tritium labeled benzene
Education
  • PhD in Organic Chemistry, 1996, University of Washington
  • MS in Organic Chemistry, 1992, University of Washington
  • BS in Chemistry, 1990, Northern Arizona University
Select Publications
  • Synthesis of Condensed N-Phenyl-Substituted Pyridinium Compounds by Reaction of Direct Phenylation with Nucleogenic Phenyl Cations. Shchepina, N. E.; Avrorin, V. V.; Badun, G. A.; Lewis, S. B.; Ukhanov, S. E Chemistry of Heterocyclic Compounds, 2012, 2, 301.
  • Synthesis of 1,3-Difluoraromatics in One Pot by Addition of Difluorocarbene from Sodium Chlorodifluoroacetate to 1,2-Substituted Cyclobutenes. *Heather M. Morrison, *James E. Rainbolt and Scott B. Lewis Org. Lett. 2002, 4, 3871.
  • Synthesis of Tritium labeled N-Phenyl-substituted Quinolinium Derivatives by Chemonuclear Synthesis. Shchepina, N. E.; Avrorin, V. V.; Badun, G. A.; Alexandrova, G. A.; Ukhanov, S. E.; Fedoseev, V. M.; Lewis, S. B.; Boiko, I. I. Chemistry of Heterocyclic Compounds, 2009, 45, 1008.

                                                                                     *indicates undergraduate student researcher

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