James Madison University

NEW COLLEGES FORMED A plan to reorganize the College of Integrated Science and Technology into two colleges took effect July 1, 2012. The new colleges are the College of Health and Behavioral Studies and the College of Integrated Science and Engineering.


Caffeine and Bone Mineral Density

Previous research suggests diets high in caffeine can have a negative effect on bone density although conflicting results have been reported in the literature.  A genetic variation of the CYP1A2 gene causes caffeine to be metabolized at a slower rate, resulting in higher levels of plasma caffeine after ingestion. Therefore, it is possible that caffeine negatively affects only those individuals with this genetic variation. This study will determine whether this genotype influences the relationship between caffeine and bone mineral density in women.  Results of this study will help clarify this ambiguous relationship and potentially provide meaningful information regarding the prevention of osteoporosis. This study is a joint project between the Nutrition and Kinesiology faculty and is supported by the CISAT Development funds and the Morrison Bruce Center for the Promotion of Physical Activity for Girls and Women.   If you would like to participate in this investigation, please contact Sandy Cubbage via email cubba2sl@jmu.edu

Participants will include:

  1. Women between ages 18-80
  2. Must not have implanted metal
  3. Must not have pacemakers

This study involves:

  • Collection of DNA via cheek swab
  • Food consumption questionnaire
  • Bone density measurement via x-ray