Carly Starke

Salmonella enterica serovar Typhi is the main cause of typhoid fever; Salmonella species cannot survive below pH 4. My proposal involves working at the Food and Drug Administration (FDA) to engineer a vaccine vector as a wafer format to survive a low pH, within the oral cavity and gastro-intestinal tract, allowing a reduction in the doses required for long-lasting, high efficacy immunity. This will be done by cloning genes involved in the acid resistance pathway of the bacterium Shigella into Salmonella. Acid resistance in these strains will be assessed compared to the parent strain at pH 1.5 to 5 over 3 hours and these acid resistance genes will be inserted into the Salmonella chromosome.

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Michelle Amaya
Health Sciences

My project proposal is intended to help me engage in a service-leadership global health immersion program called Pediatric and Adolescent Health Care. This project is to take place in La Paz, Bolivia working through Child Family Health International, an NGO. My first step will be to receive training as a Certified Nursing Assistant through the BonSecours Nurse Aide Training Program at DePaul Medical Center in Norfolk, Virginia. Following this training, I will deepen my commitment to service by engaging in a clinical rotation program through Child Family Health International, serving impoverished and at-risk children and adolescents of La Paz, Bolivia.

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