Associate Professor of Biology

B.S. - Cornell University
Ph.D. - University of Chicago

Phone - 540-568-2322
Fax - 540-568-3333
Office - Bioscience 2028C

Office hours

Courses:   Cell and Molecular Biology (BIO 214), Animal Physiology (BIO 370), Human Metabolism (BIO 472) and Human Metabolism lab (BIO 427).

Research Interests:  Biochemistry and molecular biology of glucose transport across membranes.

How do organisms use glucose? The hexose transporters of Arabidopsis thaliana belong to a super-family of proteins called major facilitator proteins, which have been identified in humans, plants and yeast. So far, of the 30 genes identified as being putative hexose transporters, 4 have been experimentally characterized. Much work is yet to be done on this large and prevalent class of proteins. Their functional diversity is thought to contribute to the metabolism of sugars under the various internal and external environmental conditions experienced by the organism. We are currently in the process of describing a salt-resistant phenotype of the developing root in seedlings of STP1 k/o plant.  Our hypothesis is that STP1 plays a role in regulating the osmotic balance in the developing root.  In addition, we show that the response of the STP1 mutant to osmotic stress induced by salt is distinct from the response to high concentrations of sugar. Projects in my lab include the study of gene expression patterns to identify relevant metabolic/signaling pathways and morphological characterization of the developing roots of the STP1 knockout plant.

Daniel, J.C., Tongen, A., Warne, D.P., Warne, P. (2009). A 3D Nonlinear Anisoptropic Spherical Inflation Model for Intracranial Saccular Aneurysm Elastodynamics.  Mathematics and Mechanics of Solids. doi:10.1177/1081286508100498. 1-20.

Neel, N., Creasy, B.M., Rankin, J.N., Pierce E.M,. McCoy, M.E., Daner, R.H., Fowler, J.A., Daniel, J.C., and Lantz, C.S.  (2004).  Absence of interleukin-3 does not affect the severity of local and systemic anaphylaxis but does enhance eosinophil infiltration in a mouse model of allergic peritonitis.  Imm. Lett. 95(1) 37-44.

Musch MW, Bookstein C, Rocha F, Lucioni A, Ren H, Daniel J, Xie Y, McSwine RL, Rao MC, Alverdy J, Chang EB. (2002). Region-specific adaptation of apical Na/H exchangers after extensive proximal small bowel resection. Am J Physiol Gastrointest Liver Physiol  Oct; 283(4):G975-85.

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