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October 2013-Quarter 2

 


 
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Monique Van Hoek

JMU Monique Van HoekTitle:

Antimicrobial activity in the bedbug, Cimex Lectularius

 

Principal Investigator:

PI: Monique Van Hoek, Ph.D., Associate Professor, School of Systems Biology, George Mason University (GMU)

Co-PI:

Ronald W. Raab, Ph.D., Professor, Department of Integrated Science and Tech, JMU

Dr. Rajeev Vaidyanathan, SRI International

Barney Bishop, Ph.D., Associate Professor, Department of Chemistry, GMU

Summary:

Bedbugs only seem to carry gram-positive bacteria and somehow exclude gram-negative bacteria. We propose to study the bedbugs for the potential expression of antimicrobial activities that can account for the depletion of gram-negative bacteria. At the conclusion of this study, we will deliver our findings of the antimicrobial activity of these blood-sucking pests. We predict that we will discover novel antimicrobial compounds, which could be developed into future antibiotics. In the long-term, these studies may improve out understanding of bedbugs that could lead to improvements in the quality of life for residents of lower-income housing. This grant meets the 4VA goals of increasing research competitiveness, and GMU’s goals of having undergraduates participate in STEM research. 

 

Awarded Funding:

$5,000 JMU

$5,000 GMU

 

Deliverables: