IACUC Faculty/Staff Training
Test Your Understanding

 
You have reached the end of the instruction on IACUC Training. Before proceeding to the test please
make sure you have reviewed all the information listed on the main training page. The questions are
drawn from all the material. Below are 20 true/false and multiple-choice questions to help check your
understanding of the process. After you have answered these questions, you will be asked to enter
information that will permit you to send your results to an e-mail address.

Click on the dot next to the best answer for each question.

  1. Why is the ethical treatment of animals important?

    2. Humans have a moral obligation to avoid causing pain or distress whenever possible
    Improving animal welfare improves the reliability of data collected from animals
    Animal welfare is mandated by law
    All of the above

  2. True or False? The IACUC physically inspects all of the institution's animal facilities
    every 12 months (on an annual basis)     .
    True
    False

  3. Which of the following is not a method of minimizing pain or distress?

    4. Using in vitro animals
    Using mechanical animals
    Using computer models
    Limiting the vision of the animals
     
  4. Which of the following is NOT included as part of animal welfare regulations?
    5. A veterinarian must provide guidance to the program
    The frequency of feeding and watering of the animals is specified
    The Animal Care and Use Committee must review protocols within 2 weeks of receipt
    Investigators should minimize the numbers of animals used
     
  5. What is the primary resource that personnel using animals are responsible for being
    familiar with?
    6. James Madison University IACUC web site.
    Animal Welfare Act
    Guide for the Care and Use of Laboratory Animals
    Animal Liberation
     
  6. Which of the following statements is TRUE?
    7. Minor changes in the protocol can be updated with the annual continuing review
    Approval of protocols is for a maximum of 3 years
    Major changes in the protocol require a new application and approval
    All of the above
     
  7. Principal investigators are responsible for?
    8. Ensuring that all animals are obtained lawfully.
    Ensuring that personnel are adequately trained in the care, handling and restraining of all
    animals used, and in the relevant experimental procedures.
    All of the above
    None of the above
     
  8. True or False? Personnel who work in laboratory animal facilities must provide proof of
    current tetanus shot.
    9. True
    False

  9. Which of the following are considered alternatives to procedures that may cause more
    than momentary or slight pain or distress to animals?
    10. Minimizing the numbers of animals needed through experimental design and appropriate
    statistical analysis of data.
    Refining procedures so they cause a minimum amount of pain or distress
    Replacing animal use with use of lower animals or non-animal models
    All of the above
     
  10. Which of the following procedures are not necessary when performing aseptic surgery on rodents?
    11. Instrument sterilization
    Preparation of the surgical site by clipping and scrubbing with a disinfectant
    Use of sterile gloves, and protective clothing
    All of the above are necessary
     
  11. True or False? Short nonsurvival surgeries must be performed aseptically.
    True
    False

  12. Which of the following are postoperative care requirements for animals that have had
    surgery?
    13. Monitoring for postoperative pain.
    Records must be maintained on animals.
    Monitoring for postsurgical infections.
    All of the above are required
     
  13. Which of the following may minimize postoperative complications from surgery?
    14. Administration of antibiotics and analgesics preoperatively
    Gentle tissue handling
    Short surgery times
    All of the above may minimize complications
     
  14. Which type of analgesic would be best for use following an abdominal surgery?
    15. A nonsteroidal anti-inflammatory drug such as ketoprofen
    An opiate such as buprenorphine
    No analgesic is needed
    A topical anesthetic
     
  15. Which of the following is NOT TRUE about anesthesia in animals?
    16. All animals respond similarly to the same drug dosages.
    Anesthetics can have profound physiological effects on animals.
    Monitoring anesthetic depth usually requires observation of several parameters.
    Loss of reflexes is a good judge of anesthetic depth

  16.  True or False? Rodent surgery has less stringent requirements than for large animals.
    True
    False
     
  17. What clinical signs are an indication that a tumor may be causing pain or distress to an
    animal?
    18. Ulceration
    Weight loss or loss of appetite
    Interference with locomotion
    All of the above
     
  18. Which of the following is/are NOT a general indication for euthanasia in research animals?
    Vocalizing
    Unrelieved pain or distress
    Disease non-responsive to treatment
    All of the above are indications for euthanasia

  19. Which of the following is not an indication that a research animal should be euthanized?
    20. General debilitation
    Infection non-responsive to treatment
    Noticeable disorientation
    Severe organ system dysfunction

  20. Which of the following statements about euthanasia is/are TRUE?
    21. Anesthetic overdose is an acceptable method
    Carbon dioxide inhalation is not a humane method to euthanize small animals.
    Administration of KCl to an awake animal is a humane method of euthanasia
    All of the above are true

     

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