James Madison University Wordmark

ISAT

Department of Integrated Science and Technology Affiliate Program

Biomanufacturing Lab

Dr. Robert McKown

The Biomanufacturing Laboratory has established capabilities for cloning and expressing foreign genes in microbial systems, pilot-scale fermentation, protein purification and analytical testing of biological molecules. The laboratory offers small-scale production of recombinant proteins for research and development on a contractual basis as well as basic and applied collaborative research projects. Established technologies include: Bacteria and yeast cell line development, propagation, and storage; Multiple biological vector systems for cloning and expressing foreign genes; Automated sterilize-in-place 10 liter fermentation; Filtration and chromatography equipment for product recovery and purification; Analytical instrumentation for the determination of product identity and purity.

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