Bioseminar: Bacillus phages variety pack: from matchsticks to giants

Fri, 17 Mar 2017 12:20 PM - 1:10 PM

Bioscience 1007

Dr. Louise Temple

Professor, JMU Dept. of Integrated Science and Technology


Viral discovery at JMU over 10 years has resulted in hundreds of novel bacteriophages, a number of which were isolated on several species of Bacillus bacteria.  Phage morphology and genome size are quite varied, possibly reflecting the year, season, and temperature of soil collection, as well as the Bacillus species and strain used as host.  We have analyzed and compared the features of over 30 genomes and conducted host range experiments across several species and strains.  Predicted endolysins have been cloned, expressed, and shown to kill Bacillus cultures.  The presentation will include a report of students at an Indian university who have participated in similar discovery based experiences.

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