CHEM 346*
LABORATORY SCHEDULE+
SPRING 2004

DATES

Experiment

Prelab Reading Assignment #

Week of Jan 12

Spectroscopy

Lecture text: Chap 13; Lab text: Appendix 3, pp. 695-712

Tues., Jan 20-Mon., Jan. 26

Spectroscopy

 

Lecture text: Chap. 14: Lab text: Appendix 4 and 5, pp.713-740

Tues., Jan. 27-Mon., Feb. 2

Spectroscopy and Intro. to the Organic Laboratory

pp. 1- 21, 671-672

Tues., Feb. 3-Mon., Feb. 9

Extraction and Crystallization

Handout, Techniques 5 and 1

Tues., Feb. 10-Mon., Feb. 16

Extraction and Crystallization (Cont.)

Techniques 2, 3 and 4

Tues., Feb. 17-Mon., Feb. 21

TBA

Week of Feb. 23

Distillation

 Handout, Techniques 6 (sec. 6.1-6.5) and 7 (sec. 7.1-7.8)

 

Week of Mar. 1

Gas Chromatography of Previous Experiment
Synthesis of p-Nitroacetanilide

Technique 12
Handout 

Week of March 8

SPRING BREAK

 

Week of March 15

MIDTERM TEST; Thin Layer Chromatography of Analgesic Drugs

Handout and Techniques 10 (sec. 10.1-10.4B) and 11

Week of March 22

Dehydration of an Alcohol

Handout and Technique 8 (sec. 8.1-8.2), and pp.509-510

Week of March 29

Kinetics

Handout

Week of April 5

Synthesis: Metalation

Handout

Week of April 12

Multistep Synthesis

Handout

Week of April 19

Multistep Synthesis (cont.)

 

Week of April 29

Multistep Synthesis (cont.) and Cleanup

 

Week of May 3

FINAL EXAM

 

*The University assesses a charge for chemicals and other consumable items used in laboratory courses.  Consequently, during the first two week of classes, each student in this course must obtain a paid "Laboratory Voucher from the bookstore.  Failure to obtain a voucher will lead to administrative course withdrawal.

+This schedule is subject to change.

#Reading assignments (unless otherwise noted) are from Pavia, D.L., Lampman, G.M. and Kriz, G.S., Introduction to Laboratory Techniques, 3rd Edition, Harcourt Brace Custom Publishers, 1988.  

Spectra for Extraction and Crystallization:

Carbon NMR of Extraction Mixture Expanded Proton NMR of Extraction Mixture
Proton NMR of Extraction Mixture IR of Extraction Mixture
Carbon NMR of Component A Carbon NMR of Component B
Proton NMR of Component A Proton NMR of Component B
Expanded Proton NMR of Component A Expanded Proton NMR of Component B
IR of Component A IR of Component B

Spectra for Distillation:

Carbon NMR of Distillation Mixture Proton NMR of Distillation Mixture
Expanded Proton NMR of Distillation Mixture IR of Component B
Carbon NMR of Component A Carbon NMR of Component B
Proton NMR of Component A Proton NMR of Component B
IR of Component A Expanded Proton NMR of Component B

Spectra for Synthesis of p-Nitroacetanilide:

Carbon NMR of Crude p-Nitroacetanilide Carbon NMR of Recrystallized p-Nitroacetanilide
Proton NMR of Crude p-Nitroacetanilide Proton NMR of Recrystallized p-Nitroacetanilide

Spectra for Dehydration of an Alcohol:

Carbon NMR of 2-methylcyclohexanol Mixture Carbon NMR of Dehydration Product
Proton  NMR of 2-methylcyclohexanol Mixture Proton NMR of Dehydration Product
IR of 2-methylcyclohexanol Mixture Expanded Proton NMR of Dehydration Product
IR of Dehydration Product

Spectra for Metalation:

Expanded Carbon NMR of Component A Expanded Proton NMR of Component B
Proton NMR of Component A Proton NMR of Component B
IR of Component A IR of Component B

Spectra for Multistep Synthesis:

Carbon NMR of Component A Carbon NMR of Component B
Proton NMR of Component A Proton NMR of Component B
IR of Component A
Carbon NMR of Component C Carbon NMR of Component D
Proton NMR of Component C Proton NMR of Component D
IR of Component D