Courses: Principles of Animal Development (BIO 316), Comparative Morphology and Evolution of the Vertebrates (BIO 320), Biology in the Movies (HON 200X), Evolutionary and Societal Impacts of Developmental Biology (BIO 450), Scientific Perspectives (GSCI 104)
My research is on the development and evolution of amphibian morphology. I am interested in amphibians because of their metamorphosis, which is a dramatic change in body form that is regulated by thyroid hormone (TH). They also have a relatively simple skeleton, much of which persists as cartilage throughout life.
Four current research projects are on the formation, growth and postembryonic development of cranial skeleton, lungs and limbs in amphibians. One project is to quantify how the individual bones and cartilages in the skulls of different species of salamanders and frogs change in shape and size as the animals grow and metamorphose. A second is to understand how the growth and shape change of cranial cartilages in one frog species (Xenopus laevis) is controlled at the level of cell behaviors like cell division and cell death and changes in cell size and shape. A third project addresses how the onset of breathing in amphibian larvae affects the development of the internal chambers of the lung and a fourth addresses how the frequency of mitosis in the limb bud changes as the limb elongates, becomes patterned and starts to differentiate. The unifying theme of my research is to better understand how cell and tissue properties and behaviors contribute to organ growth and development in animals that develop first into larvae specialized for life in water and then transform into adults specialized for life on land.
I also teach and write about the role of popular culture and movies in biology education.
Rose, C.S., D. Murawinski and V. Horne. 2015. Deconstructing cartilage shape and size into contributions from embryogenesis, metamorphosis and tadpole and frog growth. J. Anat. 226: 575-595 (doi: 10.1111/joa 12303).
Rose, C.S. 2014. The importance of cartilage to amphibian development and evolution. Int. J. Dev. Biol. 58: 917-927 (doi: 10.1387/ijdb.150053cr).
Rose, C.S. 2014. Caging, but not air deprivation, slows tadpole growth and development in the amphibian Xenopus laevis. J. Exp. Zool. 321A: 365-375.
Rose, C.S. and B. James. 2013. Plasticity of lung development in the amphibian, Xenopus laevis. Biology Open 2(12): 1324-1335 (doi:10.1242/bio.20133772).
Rose, C.S. 2009. Generating, growing and transforming skeletal shape: insights from amphibian pharyngeal arch cartilages. BioEssays 31: 287-299.
Rose, C.S. 2008. Review of “Biological Emergences: Evolution by Natural Experiment” Robert G.B. Reid. Integrative and Comparative Biology 48:871-873.
Rose, C.S. 2007. Biology in the movies: Using the double-edged sword of popular culture to enhance public understanding of science. Evol. Biol. 34: 49-54.
Wang, Y. and C.S. Rose. 2005. Jeholotriton paradoxus (Amphibian: Caudata) from the Lower Cretaceous of
Southeastern Inner Mongolia, China. J. Vertebrate Paleontol. 25(3): 523-532.
Rose, C.S. 2005. Integrating ecology and developmental biology to explain the timing of frog metamorphosis. Trends in Ecology and Evolution 20: 129-135.
Rose, C.S. 2003. Thyroid hormone mediated development in vertebrates: What makes frogs unique? In: Environment, Development and Evolution, Toward a Synthesis, G. B. Müller, B. K. Hall, R. D. Pearson, eds. Vienna Series in Theoretical Biology. Cambridge: MIT Press, pp. 197-237.
Rose, C.S. 2003. The developmental morphology of salamander skulls. In: Amphibian Biology, Vol. 5. Osteology, H. Heatwole and M Davies, ed., Australia: Surrey Beatty and Sons Pty. Ltd., pp. 1686-1783.
Rose, C.S. 2003. How to teach biology using the movie science of cloning people, resurrecting the dead, and combining flies and humans. Public Understand. Sci. 12: 289-296.