B.Sc. - University of Sydney, Australia
Ph.D. - University of Sydney, Australia
E-mail - email@example.com
Phone - 540-568-4521
Fax - 540-568-3333
Office - Bioscience 2036
Courses: Organisms Lab (BIO 114), Research Readiness (BIO 226), Microscopy (BIO432 / BIO532), Biological Illustration (BIO 426), Graduate seminar in cell and molecular biology (BIO 630)
Research Interests: Organization of the plant cytoskeleton in interphase and mitosis
In plants, the microtubule cytoskeleton has several roles. Just like in other kinds of cells, the microtubules make up the mitotic spindle and determine the cell’s shape during interphase, but in plants, the orientation of the microtubules also determines the direction in which the plant grows.
I have two main areas of interest, both concerning the microtubule cytoskeleton in plants.
The first is: how do plant cells grow together in a co-ordinated way? This must involve cell-to-cell communication and intercellular organization of the cytoskeleton so that all the cells grow in the same direction.
The second is: How different is plant mitosis from animal mitosis? The spindles themselves look slightly different between phyla, and very few of the molecular mechanisms are known in plants. There is evidence that many of the same motors that are important for mitosis in animal cells also play a role in plant mitosis, but there is still much to be learned. Also, mitotic checkpoints are relatively unexplored in plants. Some that are well known in animal systems could be different or absent in plants.
I have been investigating these questions, primarily through microscopy, with two arabidospsis mutants: rsw6, which is defective in intercellular microtubule alignment, and rsw7, which lacks a crucial mitotic motor protein.
Bannigan, A., Lizotte-Waniewski, M., Riley, M., Baskin, T.I. (2008) Emerging molecular mechanisms that power and regulate the anastral mitotic spindle of flowering plants. Cell Motil. Cytoskel. 65(1):1-11
Bannigan, A., Scheible, W-R., Lukowitz, W., Fagerstrom, C., Wadsworth, P., Somerville, C. and Baskin, T.I. (2007) A conserved role for kinesin-5 in plants. J. Cell Sci. 120: 2819-2827
Nguema-Ona, E., Bannigan, A., Chevalier, L., Baskin, T.I. and Driouich, A. (2007) Communication between cytoplasm and cell wall: binding arabinogalactan-proteins disorganizes cortical microtubules in the root of Arabidopsis thaliana. Plant J. 52(2): 240-251.
Rahman, A.; Bannigan, A.; Sulaman, W.; Pechter, P.; Blancaflor, E.; Baskin, T. (2007)Auxin, actin, and growth of the Arabidopsis thaliana primary root. Plant J. 50(3): 514-528
Bannigan, A.; Wiedemeier, A.M.D.; Williamson, R.E.; Baskin, T.I. & Overall, R. (2006) Cortical Microtubule Arrays Lose Uniform Alignment between Cells and Are Oryzalin Resistant in the Arabidopsis Mutant, radially swollen 6. Plant & Cell Physiology 47(7)
Bannigan, A. & Baskin, T.I. (2005) Directional cell expansion - turning toward actin. Current Opinion in Plant Biology 8(6):619-624