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Courses:
Organisms Lab (BIO 114), Human Anatomy
(BIO 290), Human Embryology (BIO 416), Scientific Presentations
(BIO 603)
Research
Interests: Biochemical
Analysis of Healing and
Nonhealing Wounds.
Chronic wounds (ulcers) compromise the health and
quality of life for
millions of people in the United States suffering from various diseases
(e.g., diabetes) and disabilities (e.g., paralysis). Although chronic
wounds develop for many reasons, they are thought to persist due to an
imbalance of growth factors, enzymes, and enzyme inhibitors secondary
to decreased blood flow. My lab uses cell and molecular biology
techniques to identify relevant protein and mRNA levels within the
wound before and after treatment. Ultimately, I hope to develop a
simple and inexpensive assay to assist the clinician in assessing the
efficacy of the chosen treatment prior to observing visual changes in
wound health. Such information will benefit patients with chronic
wounds, the clinicians’ choice of intervention, and the economics
associated with treatment. Students working in my lab will have the
opportunity to acquire commonly used cell and molecular biology
techniques and to use these techniques to answer questions regarding
the biochemistry of healing and nonhealing wounds.
Selected
Publications:
Jaynes CD, Fries K, Brogan MS, Karch JE, Baird K,
Edsberg LE.
Development of a protocol for biochemical analysis of wound fluid
proteins. Acute Care Perspectives, 12:1 (2003) 11-15.
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