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Marta Bechtel
Assistant Professor of Biology
B.S. - California State University, Long Beach
Ph.D. - University of Southern California Keck School of Medicine
E-mail - bechtemk@jmu.edu
Phone - 540-568-5526
Fax - 540-568-3333
Office - 109 Burruss
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Courses:
Cell and Molecular Biology (BIO 214)
Research Interests: Molecular biology and mechanical
properties of cartilage tissue.
A recent research focus is studying cartilage
tissue as a tissue engineering model system to better understand basic
cell and molecular biology of chondrocytes, the cell population present
in cartilage tissue, and to learn more about the biomechanical
properties of cartilage tissue. This research also has applications in
understanding the molecular mechanisms associated with the
pathophysiology of osteoarthritis (OA), a disease involving the
progressive degeneration of cartilage tissue. In healthy
cartilage a balance exists between degradation and repair processes
that maintain cartilage tissue integrity and facilitate healing.
However, in OA this balance is disrupted and degradation is
predominant. OA is a complex, multi-factorial disease, so a better
comprehension of the modulating factors and major regulatory networks
associated with the etiology of OA is an important priority of this
research effort.
Selected
Publications:
Bechtel, M. K., and B. Bonavida. 2001.
Inhibitory effects of 17β-Estradiol and progesterone on ovarian
carcinoma cell proliferation: a potential role for inducible nitric
oxide synthase. Gynecol. Oncol. 82: 127-138.
Bechtel, M. K., L. E. Mathes, K. A. Hayes, R. Pandey, and P.
Roy-Burman. 1999. Recombinant feline lukemia Virus (FeLV) variants
establish a limited infection with altered cell tropism in specific
pathogen-free cats in the absence of FeLV subgroup A helper virus. Vet.
Pathol. 36: 91-99.
Bechtel, M. K., L. E. Mathes, K. A. Hayes, A. Phipps, and P.
Roy-Burman. 1998. In vivo evolution and selection of recombinant feline
leukemia virus species. Virus Res. 54: 71-86.
Chen, H., M. K. Bechtel, Y. Shi, A. Phipps, L. E. Mathes, K. A. Hayes,
and P. Roy-Burman. 1998. Pathogenicity induced by feline leukemia
virus, Rickard strain, subgroup A plasmid DNA (pFRA). J. Virol. 72(9):
7048-7056.
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For information contact:
Sheila Santee
540-568-6225 or 6733
Dept. Fax:
540-568-3333
Web site maintained by:
Jon Monroe
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Mailing address:
Department of Biology
MSC 7801
James Madison University
Harrisonburg, VA 22807 USA |
Express mailing address:
Department of Biology
Burruss Hall, Room 243
James Madison University
Harrisonburg, VA 22807 USA
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@ 2005-2008,
Department of Biology. All rights reserved. Privacy
Statement
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